Lindsay Dresang, Ph.D.

Assistant Professor of Biology

Office: CBB 313
Phone: (715) 346-2627
Fax: (715) 346-3624
Email: LDresang@uwsp.edu
 
 

Academic Background

2010-2013:  University of Pittsburgh Cancer Institute
Post-Doctoral Fellow in the Chang-Moore Lab

2005-2010:  University of Wisconsin–Madison, School of Medicine and Public Health
Ph.D. in Cancer Biology
Graduate Research in the Sugden Lab

2003-2005:  University of Wisconsin–Madison, College of Agricultural Sciences
B.S. in Natural Sciences, Genetics
Undergraduate Research in the Weichert Lab

2001-2003:  University of Wisconsin–Fox Valley (University of Wisconsin–Oshkosh dual enrollment spring 2002)

Courses

BIOL 101 – General Biology (Lab Instructor)
BIOL 160 – Introduction to Animal Biology
BIOL 287 – Essentials of Human Anatomy
BIOL 313 – Cancer Biology
BIOL 315 – Virology
BIOL 381 – Animal Physiology (Lab Instructor)
BIOL 385 – Human Physiology (Lab Instructor)
BIOL 387 – Human Anatomy
BIOL 399 – Research in Molecular & Cellular Biology (Cancer Biology / Virology)
BIOL 399 – Teaching Assistant (Human Anatomy)
BIOL 399 – Independent Study (Dissection)
BIOL 487 – Survey of Human Dissection
BIOL 490 – Senior Seminar in Cancer Biology
BIOL 490 – Senior Seminar in Virology
 

Professional Affiliations & Honor Societies

American Association for Anatomy (AAA)
Human Anatomy & Physiology Society (HAPS)
Faculty of 1000 Prime, Peer Reviewer (F1000)
Gamma Sigma Delta, Honor Society in Agricultural Sciences (ΓΣΔ)
Phi Theta Cappa, Two-year Colleges Honor Society (ΦΘΚ)

Research Interests

Cancer Biology:
My research goals are to address how select cancer cell lines are prone to metastasize to the liver in an immunocompromised mouse model.  There are hundreds of different types of cancers because there are hundreds of types of differentiated cells in the human body.  Within the same cancer type, there can be considerable variation between individual tumors in terms of malignancy and metastatic potential.  I am interested in assessing multiple cancer types using paired sets of individual cancer cell lines which either do or do not metastasize to the liver in immunocompromised mouse models.  Using several cancer cell types with this metastatic / non-metastatic pairing should allow me to assess which cell signaling pathways may influence metastatic potential.  Slowing metastatic progression may not eliminate cancer, but it could help stabilize the disease.
 
Virology: (under construction)
In my postdoctoral and graduate research training, I studied multiple human tumor viruses, including Epstein Barr virus, Kaposi’s sarcoma-associated herpesvirus, and Merkel cell polyomavirus. Many additional viruses were also researched in an ancillary capacity. I am interested in exploring viral-host interactions, particularly those involving transcription and DNA-binding.
 
Teaching-As-Research: (under construction)
Students may serve as teaching assistants in Human Anatomy (Bio 399) during fall semesters, and possible over the last 6-week session in summer.  Students must have earned at least a B in Human Anatomy to serve as a Bio 399–Human Anatomy TA.  Students may then have the opportunity to design a project assessing student learning and/or student appreciation of Human Anatomy. 
 

Select Publications

First Author:
2013Dresang LR, Guastafierro A, Arora R, Normolle D, Chang Y, Moore PS. Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma Mouse Xenografts Respond to YM155 Treatment in a Dose, Duration, and Cell Line Dependent Manner. PLoS One 8(11):e80543.
2011Dresang LR, Teuton JR, Feng H, Jacobs JM, Camp DG 2nd, Purvine SO, Gritsenko MA, Smith RD, Sugden B, Moore PS, Chang Y. Coupled Transcriptome and Proteome Analysis of Human Lymphotropic Tumor Viruses: Insights on the Detection and Discovery of Viral Genes. BMC Genomics 12(625).
2009Dresang LR, Vereide DT, Sugden B. Identifying Sites Bound by Epstein Barr Nuclear Antigen 1 (EBNA1) in the Human Genome: Defining a Position-Weighted Matrix to Predict Sites Bound by EBNA1 in Viral Genomes. J Virol 83(7):2930-2940.
​Faculty of 1000 Reviews:
2013Moore PS, Feng H, Dresang LR. Decoding human cytomegalovirus.
2012Moore PS, Dresang LR. Direct and efficient cellular transformation of primary rat mesenchymal precursor cells by KSHV.
2011Moore PS, Dresang LR. Discovery of a viral NLR homolog that inhibits the inflammasome.